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Only consider this option under the guidance of a doctor or pharmacist. Offers the same effectiveness in treating erectile dysfunction (ED) without paying a premium for the brand name. The choice between Sildenafil 100mg and 50mg depends on several factors, including the severity of your condition, medical advice, and your personal preferences. This is especially true when a woman is on the verge of menopause.

Read the drug information contained in the package from the drug manufacturer. If you don’t understand the instruction on how to take Viagra, ask your healthcare provider or pharmacist to explain. For this reason, a person who is 65 years of age or older may be started on a lower Viagra dose, typically 25 mg. In contrast, a young man with no significant health conditions is usually prescribed Viagra 50 mg as a starting dose. Also, men taking certain medications called alpha-blockers may need to take a lower dose of viagra 50mg pfizer. Alpha-blockers are used to lower blood pressure and treat prostate disease (e.g., tamsulosin (Flomax), prazosin (Minipress), and doxazosin (Cardura)).

Rarely, sildenafil can cause temporary color vision changes. If you have an eye condition called retinitis pigmentosa, check with your healthcare provider before using PDE5 inhibitors like sildenafil. It may also increase the risk of non-arteritic ischemic optic neuropathy (NAION) in some people––this is an eye problem that can lead to vision loss.

It is important to take this medication exactly as prescribed by your doctor. Do not take higher doses of this medication than those prescribed by your doctor. Contact your doctor if you take a greater dose of sildenafil than prescribed. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

However, you should always be open and honest in the medical questionnaire before progressing with your treatment. For example, if you’ve had a cardiac issue such as a stroke or heart attack in the previous 6 months, PDE5 inhibitors like Sildenafil and Tadalafil should be avoided. It’s important to give a true account of your health and medical history – to allow your clinicians to supply safe medication for you. You can get sildenafil on the NHS if you have certain medical conditions, such as diabetes. If you require more than this, you are required to obtain treatment privately.

The major circulating metabolite results from N-demethylation of sildenafil. This metabolite has a phosphodiesterase selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% that of the parent drug. Plasma concentrations of this metabolite are approximately 40% of those seen for sildenafil. The N-desmethyl metabolite is further metabolised, with a terminal half-life of approximately 4 h. When sildenafil is taken with food, the rate of absorption is reduced with a mean delay in tmax of 60 minutes and a mean reduction in Cmax of 29%. In cases of overdose, standard supportive measures should be adopted as required.

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